Alexis Arquette — the transgendered actress who was once brother/sister-in-law to
Courteney Cox — shocked friend and fans with his sudden death on Sept. 11, 2016, at the age of 46. "None of us knew that she had gotten so sick," a close pal told The National ENQUIRER, although the actress passed while surrounded by her family. That included her brother
David Arquette, Oscar-winning actress
Patricia and sister
Rosanna. Patricia issued a statement that Alexis (born as Robert) had passed away surrounded by her siblings as they serenaded her with a song by
David Bowie. But while the flamboyant Hollywood actress was beloved for her outspoken ways, she also died feeling betrayed by the gay community!