NATALIE WOOD’s tragic death remains one of Hollywood’s most enduring mysteries – and The ENQUIRER has uncovered new evidence that could blow the lid off the decades-old case.

In a stunning exclusive, we reveal that investigators have taken a fresh look at Wood’s autopsy report and are now pursuing a new theory that could implicate her husband Robert Wagner.

Wood was just 43 when she drowned on the night on Nov. 29, 1981 while she and Wagner entertained her “Brainstorm” co-star Christopher Walken aboard their yacht “Splendour” near California’s Catalina Island.

Authorities initially ruled the death an accident, and Wagner has steadfastly insisted that no foul play occurred that fateful night.

But police reopened the investigation in 2011 and eventually took the unprecedented step of reclassifying the death from “accidental drowning” to “drowning and other undetermined factors.”

And now, an overlooked element of the autopsy supports the possibility that the raven-haired screen beauty’s death was indeed no accident – and a source divulged that cops have found new witnesses who “support a key individual’s claims that have been made against Robert Wagner.”

Although cops continue to say that Wagner is not a suspect in the case, one nationally known law enforcement expert told The ENQUIRER that Wagner’s status could change.

To find out what new evidence was gleaned from the autopsy report and how it could change the course of the investigation, pick up the latest issue of The ENQUIRER – on sale now!