Brad Pitt & George Clooney: From Best Friends To Backstabbers!

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BRAD PITT and GEORGE CLOONEY – the Hollywood hunks who were once palsy-walsy in “Ocean’s Eleven” and its sequels – are now mortal enemies!

The two Oscar winners are “at each other’s throats” over a big-bucks business deal that went Brad’s way, sources revealed exclusively to The National ENQUIRER.

The bad blood boiled over when Brad’s company, Plan B, beat out George’s production arm for a highly coveted film project.

To George’s disgust, Brad won the film rights to a book about an American lawyer’s crusade against Big Oil on behalf of the poor farmers in the Amazon rainforest.

The book, “Law of the Jungle,” chronicles the true-life story behind the 22-years-and-counting legal battle over pollution in the Ecuadorian jungle.

The lawyer eventually won an $18 billion judgment against corporate colossus Chevron.

“George desperately wanted the project. Brad knew it, but he scooped it up anyway. He told George, ‘It’s just business, man,’” a source said.

“But George can’t forgive him. He thinks Brad’s a big phony now – praising him to the press and then stabbing him in the back!”

Just last year, Brad, 51, gushed over the 54-year-old silver fox, declaring: “Well, you know, George is one of our best representatives. He’s a joy to be around.”

But, said the insider: “Brad no longer feels that way about George. He can’t stand the sight of him anymore. He told him to his face, ‘I hate you! Drop dead!’”

Even the guys’ beautiful brides – Angelina and Amal – reportedly hate each other now.

Said the source: “Angie thinks Amal is ‘putting on airs,’ and Amal thinks Angie is a pretender.”