TATUM O’NEAL’s ongoing drug addiction battle has family and friends worried as new fears have emerged.

"Since Tatum has been out of rehab she has been absolutely estranged from most of her family, including her children and her father," a source close to family told RadarOnline.com

"Her family and friends are very concerned about her well-being and they fear for her. She has developed an addiction to prescription pills.

“Tatum didn't spend Mother's Day with her children, and she truly is her own worst enemy right now," the source added.

The Oscar-winning “Paper Moon” star, 48, recently went back to rehab after a full blown cocaine relapse.

As The ENQUIRER reported previously Tatum has battled drug addiction for most of her adult life.

Recently, Tatum and her half-brother Redmond had both slammed dad Ryan O’Neal's memoir “Both Of Us: My Life With Farrah” because they claim it’s not an honest account, promoting what they described as "Ryan's self-serving narcissistic tendencies," according to a source.The son of Farrah Fawcett and Ryan O’Neal, Redmond is also currently in rehab in Southern California for an addiction to heroin.