Hollywood royalty DEBBIE REYNOLDS, 80, has been rushed to the hospital as fans worldwide fear the worst!

The “Singing in the Rain” star who famously lost hubby Eddie Fisher to BFF Liz Taylor in the 1950s was rushed to Cedars Sinai hospital in Los Angeles.

According to her rep, the emergency trip was the result of an adverse reaction to a prescription medication.

"Debbie was hospitalized at Cedars Sinai in Los Angeles due to an adverse reaction she experienced to a medication she was currently taking," her rep said in a statement.

"On the advice of her doctors, Reynolds has been forced to cancel appearances and concert engagements for the next three months."

The still perky star star maintains a prolific live concert tour schedule, her rep said.  She still hopes to make her scheduled appearance in the Tournament of Roses Parade on New Year’s Day.

For those that don’t know — Debbie has had a long strange relationship with troubled daughter Carrie Fisher of “Star Wars” fame.

We wish Our Miss Reynolds a speedy recovery.