Skeletal Angelina Jolie — Her Bone Disease Hell

The National ENQUIRER caught Angelina Jolie flying out with kids Knox and Maddox — while looking more fragile than ever! The scary-skinny star is weighing an all-time low of 79 lbs., with medical experts fearing that the beauty is facing a major health crisis!

Top doctors say that Angie is now at risk of developing arthritis and the debilitating brittle bone disease osteoporosi. That has husband Brad Pitt worried that his wife's days are numbered! “Angie may be dealing with osteoporosis, and Brad feels like he’s watching his wife slowly die right before his eyes!” cried a concerned insider.

As The ENQUIRER has reported, experts said the 41-year-old mother of six may be suffering from what “appears to be anorexia.” Anorexia and low body weight are key risk factors for osteoporosis, which causes bones to weaken and lose density. Putting Angie at even greater peril, she went into early menopause when she had her ovaries removed in 2015 after discovering ovarian cancer markers!

Osteoporosis is more common in women after menopause, but research shows that those who go through early menopause are almost twice as likely to have the disease. Early menopausal women like Angie are also at greater risk of fractures and an increased death rate, according to a study conducted at Sweden’s Skane University Hospital.

“Brad fears an activity as innocuous as roughhousing with the kids could lead to a fracture!” the source told The ENQUIRER. Angie may also suffer from rheumatoid arthritis, said a source. Its symptoms include fatigue, joint stiffness and pain, swelling and tingling sensations.

“Her hands have the gnarled, veiny appearance of an older person with arthritis,” added the informant. “Her elbows and knees are also knobby. Brad can’t believe all this could happen to the sexy seductress he fell in love with!”