Feud heats up among former "FRIENDS" MATTHEW PERRY and JENNIFER ANISTON – right out of an ep of MATT LEBLANC’s “Episodes”!   Life imitates art?

IT turns out Jennifer Aniston isn’t such a good “Friend” after all. Just ask Matthew Perry. Jennifer has turned down repeated pleas from her former TV co-star to make a guest appearance on his new NBC show “Go On,” say sources.

Her excuse: She’s too busy.

“Jen gave Matt the complete brush-off when he came calling for help,” disclosed an insider.

“He’s desperate to get his career back on track, and of all his old co-stars, Matt knew Jen is in the best position to help because she’s had the most success.

“He even told network brass he’d have no problem convincing her to at least do a cameo. But now that she’s blowing him off, Matt feels like a fool.”

While the screen queen , 43, is still making movies in spite of bad reviews and disappointing box-office sales, Matt’s career has fared much worse with a few short-lived TV shows.

Matt kept on asking if Jen would commit to a guest stint on an episode or two, and for weeks she wouldn’t give him a concrete answer,” said the source.

“He asked Courteney Cox too, but she said ‘no’ right away because she thought it would conflict with her work on ‘Cougar Town.’ When he went back to Jen and said he needed an answer pronto, she finally said, ‘Sorry, I can’t. I’m too busy.’ ”

It was an especially low blow to Matt because he desperately needs a hit show.

 “Matt is really angry at Jen for abandon­ing him when he needs her help the most,” the insider divulged.

Ironically, on Matt LeBlanc’s hit Showtime show “Episodes” where he plays a thinly disguised version of himself a key ep this season revolved around Matt trying to lure his “Friends” to guest on his make-believe sitcom “Pucks”.

He finally got ONE but our lips are sealed as to WHICH one.