JENNIFER ANISTON has had enough of her “We’re the Millers” co-star EMMA ROBERTS because of the starlet’s out-of-control behavior, sources say.

“Jen totally disapproves of Emma’s hard partying and public blowups,” an insider told The ENQUIRER. “She’s even told Emma that unless she shapes up, she may not be invited back for a possible ‘Millers’ sequel.”

Emma, the 22-year-old niece of America’s sweetheart Julia Roberts, was busted for domestic violence in Montreal in July after an alleged scuffle with boyfriend Evan Peters, star of TV’s “American Horror Story.” Emma was released after questioning, and the case was closed.

The “Nancy Drew” cutie also got slammed for trying to cut in line at legendary New York bakery Dominique Ansel in August. And a while back, she reportedly had to be carried from a Michigan nightclub after partying up a storm at her “Scream 4” co-star Hayden Panettiere’s 21st birthday party.

“Jen’s known Emma since she was 12,” said the insider.

“It’s sad because Jen’s been backing her career all the way. Jen’s an old pro, and the crazy headlines about Emma and her diva behavior just don’t sit well with her.”

As The ENQUIRER has reported, Emma’s concerned Aunt Julia also planned an intervention for her wild-child niece.

“Julia’s tried everything,” said the source. “She’s even gotten Emma into meditating, but Emma’s losing allies fast.”

MEANWHILE, with “We’re The Millers” banking around $180 million worldwide, Aniston is looking to launch a possible franchise with the raunchy R-rated comedy, said the insider.

“And she’s not going to have her plans sidetracked by someone who’s not in control of their PR,” added the source. “That’s a showbiz basic.”