As The ENQUIRER FIRST reported MICHAEL DOUGLAS and CATHERINE ZETA-JONES are headed for a $300 million divorce, say sources.

In our new print edition on sale today blockbuster new photos show for the first time the loneliness of Michael Douglas and Catherine Zeta-Jones as the A-list Hollywood couple lead totally separate lives getting ready for what sources say will be a $300 million divorce.

The warring superstars haven’t been photographed together since an April 22 awards gala in New York City, and in our Aug. 26 issue we revealed that friends pre­dict a custody battle could erupt over the couple’s children – son Dylan, 13, and daughter Carys, 10.

While Catherine’s reps deny re­ports of trouble in the marriage, it’s clear the once-tight duo are definitely apart.

Michael, 68, has been trying to take his mind off his marriage by spending a few days in late August on a pal’s luxury yacht off the coast of Sardinia, Italy.

THE ENQUIRER first BROKE THE NEWS that their marriage buckled in the summer of 2012, with sources blaming the pressure of dealing with Michael’s cancer battle, his druggie son Cameron’s incarcera­tion and Catherine’s struggle with a bipolar disorder.

“Michael and Catherine are headed toward a $300 million divorce,” said a family friend.

For the FULL Story with ALL the DETAILS and to see EXCLUSIVE PICTURES – it’s only in the new ENQUIRER – ON SALE NOW!