Brave Christina Applegate’s Double Baby Joy!

Sexy star Christina Applegate is determined to have another baby by any means — and she won’t let cancer stand in the way!

The 43-year-old former “Married With Children” star and rocker husband Martyn LeNoble — parents to 4-year-old daughter Sadie — have scrapped plans to have another biological child, and are instead forging ahead with adoption.

“Christina has been inspired by her A-list friends who have adopted, including Sheryl Crow, Charlize Theron and Sandra Bullock, as well as Angelina Jolie,” a source close to the couple told The National ENQUIRER.

“There’s never been a doubt in Christina’s mind that she and Martyn would love to raise another baby. But with Christina’s age and her cancer history, her hopes were dimming.”

Christina underwent a double mastectomy in 2008 after doctors found cancer cells in her left breast and discovered that she also carries the BRCA gene, which makes her more susceptible to breast and ovarian cancer.

Angelina, who also carries the BRCA gene, underwent a preventive double mastectomy in 2013, and this year she had her ovaries and fallopian tubes removed. Three of her six children were adopted.

As The ENQUIRER reported in September, after fearing they were too old to be second-time parents, Christina and Martyn, 46, recently had an about-face.

“Christina wasn’t sure she and Martyn would have the stamina to handle another newborn. And she was initially turned off by how lengthy and complicated the adoption process can be,” said the source.

“But after consulting with Charlize, Sheryl and Sandra, Christina changed her mind. They all raved about how welcoming an adopted child expanded their hearts and worldview. It’s a new chapter Christina is ready to dive into.”

But she still faces other issues.

“Christina thinks it’d be best for her health and for her expanding family if she played it safe and had her ovaries removed before their little bundle of joy arrives,” added the source.