BRAD PITT and ANGELINA JOLIE‘s  heartbreaking new family crisis – tormented by speculation  their 21-month-old twins are suffering  from Down syndrome.

The Hollywood superstars are  grappling with online chatter  about babies Knox and Vivienne, and bloggers say the children appear to have the developmental disorder.

Children with the Down syndrome genetic disorder are detected by developmental delays — physical characteristics, include rounded face, flattened profiles and upward slanted eyes.

And it’s those descriptions that have sparked the false online speculation.

"Brad and Angie would subtly try to degstimatize the issue by not hiding them," a close family friend said.

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