Weeds costars Mary Louise Parker and Jeffery Dean Morgan have said finis to their engagement.

The 43 year-old Parker has sent 41 year-old lover and costar Morgan packing.

Back in 2006, the couple met on the set of the Showtime comedy series and promptly began dating. Last summer, the dyspeptic duo split briefly but soon reconciled, with nuptials pending for later this year.

According to an insider, Parker cited differences in lifestyles between the two, hoping that she and Morgan would remain friends.

Oddly enough, characters played by Morgan have died on three separate television series — Grey's Anatomy, Supernatural and, of course, Weeds.