Oprah Winfrey is caught up in a sex scandal involving a close friend — and it’s not only hurt her personally but impacted her professional life as well.

The scandal erupted when Oprah found out the friend was cheating on his wife — who’s also very close to the talk show queen. Now Oprah and the friend — who has helped her with her business empire for years — are going their separate ways.

The issue that goes on sale Friday reveals how Oprah was devastated by her friend’s cheating, how the friend tried to sabotage her relationship with fiance Stedman Graham … and more.

Pick up your copy of The ENQUIRER today!