BRANGIE $250 MIL BREAK-UP!

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Brad Pitt and Angelina Jolie are heading for one of the messiest, most expensive breakups in Hollywood history!

With Brad looking after their kids 24/7 while Angelina throws herself into work, their relationship has been stretched to the breaking point, insiders tell The ENQUIRER.

Now family and friends expect a heartbreaking battle for their six children, and sources predict a titanic fight over their massive $250 million fortune.

"Brad and Angelina have been leading increasingly separate lives, and Brad has had enough of being a full-time dad," maintained an insider. "He’s visited Angelina only once on the New York set of her latest movie, and he genuinely feels they no longer have the equal relationship they once did."

As one of Tinsel Town’s top A-list couples, Brad pulls in up to $35 million a film, while Angelina banks around $20 million per movie. Sources say dividing their tangled assets is sure to be a legal minefield.

But as Brad, 45, and Angelina, 33, brace for a possible split, the issue of child custody is causing the greatest heartache, sources say.

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